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What to do if the dog has uremia?

Date: 2024-01-21

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What to do if the dog has uremia?
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Hospital admission treatment for dog uremia:

1. General treatment. Sodium bicarbonate is administered according to the degree of acidosis (detection of plasma carbon dioxide binding capacity), and calcium-free infusions are selected to adjust hyperkalemia. Supplement a large number of amino acids and high energy, vitamin preparations, etc. to improve hypernitremia

2, take peritoneal dialysis. When blood urea nitrogen is 100 mg/100 ml, serum creatinine is 10 mg/100 ml, and serum potassium is 6 mmol/L, peritoneal dialysis can be purchased.

3. Intermittent peritoneal perfusion: the abdominal wall is clipped and disinfected, punctured with an ascites trocar, and inserted with a multi-hole cannula. The cannula was removed and the cannula was left in place. After the perfusate is warmed, inject 50-150 ml/kg each time, stay for 40 minutes, drain naturally, and repeat 2-3 times. The perfusate is usually compounded with sodium lactate.

4. When the dog's pulmonary edema is severe, use a combination of glucose and sodium lactate with high osmotic pressure.

Causes of uremia in dogs:

1. Absorption of intestinal toxic substances, such as phenol, tyramine, phenylethylenediamine, etc., after being absorbed into the blood from the intestinal tract, due to renal failure and decreased liver detoxification function, the toxic substances accumulate in the blood and cause poisoning.

2. Due to renal failure, urea enters the intestinal cavity, is decomposed by intestinal bacteria into ammonia and ammonium salt, and then absorbed into the blood, causing symptoms of neurotoxicity.

3. Some toxic products of protein decomposition, such as the accumulation of guanidine compounds, can inhibit the activity of certain enzymes (lactate dehydrogenase, ATPase, etc.) in the body, thereby causing convulsions in dogs, and can also induce gastroenteritis and pericarditis in dogs , bleeding and decreased immune function.

4. Acidosis occurs due to acidic metabolite excretion disorder, causing changes in breathing, cardiovascular activity and coma.

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