When Do Dog Vaccines Fail?

Reasons for dog vaccine failure:

1. Insufficient antibodies lead to vaccine failure. Generally speaking, when the serum antibody titer is greater than 10 international units per milliliter, infectious diseases can be prevented. About 30% of the dogs have antibodies 1 month after the vaccination, and the antibodies reach the highest level 1 month after the full course of injection. Therefore, before all the injections are completed, if the antibody is not produced or the titer is relatively low, there is still the possibility of infection. Dogs must still receive other close precautions during this time.

2. Poor health causes the vaccine to fail. Sick dogs cannot be vaccinated. For example, if the parasites are not cleaned up or have a high fever, the vaccination at this time will cause immune disorders.

3. Has been infected with the virus and the vaccine is invalid. Dog vaccines are generally vaccinated before the comprehensive physical examination. Although the indicators are normal, they may still be in the incubation period of the disease and cannot be detected. The antibodies produced by the vaccine are only effective against the virus in the blood, not against the virus that has entered the cells. Therefore, if the vaccine has been infected with the virus before the injection, the injection will not work.

4. The mutation of the virus makes the vaccine invalid. Even if the vaccination produces a high titer of antibodies, a small number of dogs may still get sick. This is because viruses can mutate, and existing vaccines target normal viruses. If the surface antigen of the virus has mutated, the vaccinated dog is unfortunately infected with this mutant virus, and it is still possible to get sick.

5. Improper injection of the vaccine leads to the failure of the vaccine. Many doctors will inject dogs in the buttocks, and the vaccine should not be injected in the buttocks. Because there is more adipose tissue in the buttocks and less immune active cells, the antibody titer produced after injection is low, and the antibody declines quickly.

6. Improper timing of vaccine injection will cause the vaccine to fail. Too early most of the time. When antibodies are injected multiple times, some antigens are removed. Of course, the function that can be produced will be greatly reduced, or if the annual vaccination is not followed by the doctor's instructions, of course there is also the possibility of infection, because the effect of the vaccine can only last for one year.